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weights in mixed modelling

Hi Alex,

The analysis that you're working on sounds like what would be called an
"individual participant data meta-analysis." You might find the literature
on that topic helpful in thinking about analytic approaches.

In the meta-analysis literature, there's been quite a bit of discussion
about the idea of using weighting as a means to address issues of variable
study quality. My sense of it is that the consensus in the meta-analysis
context is that weighting by study quality is not recommended. Two papers
to give you a flavor of the discussion:
https://doi.org/10.3102/1076998610393968
https://doi.org/10.1093/biostatistics/2.4.463

An alternative to using study-quality weights would be to use the study
quality index (or perhaps the sub-components of the index) as predictors in
your analysis. This would allow you to, for example, make predictions about
whatever the target quantity of interest would be in a (hypothetical) study
that had a perfect quality index.

Kind Regards,
James

On Thu, Jan 14, 2021 at 11:03 AM Baecher,Joseph Alex <jbaecher at ufl.edu>
wrote:

  
  
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