linear mixed model required for the U.S. FDA
Please do check all parameters. I recall that SAS and R use a different style of dummy coding factor variable. If that is not the case, please write the full equation for the SAS model. The language of mathematics is the best way to clearly describe a model and thus to compare models. Best regards, ir. Thierry Onkelinx Statisticus / Statistician Vlaamse Overheid / Government of Flanders INSTITUUT VOOR NATUUR- EN BOSONDERZOEK / RESEARCH INSTITUTE FOR NATURE AND FOREST Team Biometrie & Kwaliteitszorg / Team Biometrics & Quality Assurance thierry.onkelinx at inbo.be Havenlaan 88 bus 73, 1000 Brussel www.inbo.be /////////////////////////////////////////////////////////////////////////////////////////// To call in the statistician after the experiment is done may be no more than asking him to perform a post-mortem examination: he may be able to say what the experiment died of. ~ Sir Ronald Aylmer Fisher The plural of anecdote is not data. ~ Roger Brinner The combination of some data and an aching desire for an answer does not ensure that a reasonable answer can be extracted from a given body of data. ~ John Tukey /////////////////////////////////////////////////////////////////////////////////////////// <https://www.inbo.be> Op ma 19 aug. 2019 om 13:30 schreef Helmut Sch?tz <helmut.schuetz at bebac.at>:
Dear Thierry, amazing! However, the PE obtained by exp(summary(model3)$fixed["treatmentT", "mean"]) is with 1.157428 even more off from the /desired/ 1.1565764 than lmer?s 1.1572982. Best, Helmut -- Ing. Helmut Sch?tz BEBAC ? Consultancy Services for Bioequivalence and Bioavailability Studies Neubaugasse 36/11 1070 Vienna, Austria W https://bebac.at/ C https://bebac.at/Contact.htm F https://forum.bebac.at/