Dear Xiyue,
Don't think in terms of cells but in terms of observations. The model tries
to minimise the residuals. So combinations with more observations have more
residuals and thus a stronger impact on the MSE.
Best regards,
ir. Thierry Onkelinx
Instituut voor natuur- en bosonderzoek / Research Institute for Nature and
Forest
team Biometrie & Kwaliteitszorg / team Biometrics & Quality Assurance
Kliniekstraat 25
1070 Anderlecht
Belgium
To call in the statistician after the experiment is done may be no more
than asking him to perform a post-mortem examination: he may be able to say
what the experiment died of. ~ Sir Ronald Aylmer Fisher
The plural of anecdote is not data. ~ Roger Brinner
The combination of some data and an aching desire for an answer does not
ensure that a reasonable answer can be extracted from a given body of data.
~ John Tukey
2016-10-12 19:48 GMT+02:00 Xiyue Liao <liaoxiyue2011 at gmail.com>:
Hi,
I'm using lmer in the R package lme4 to do a one-way anova analysis with a
fixed effect term and a random effect term. So the fixed effect is about
four medical conditions and the random effect is about randomly sampled
donors. Now for some combinations of donors and medical conditions, there
are more than one measurement, which makes the whole design unbalanced. I
think that lmer can handle such a case, and I have run the code without any
error message. However, I don't understand how this routine put weight on
the cells with more measurements than other cells. Could you give me some
hint?
Thanks in advance for your help.
Sincerely,
Xiyue
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