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distribution of random effects glmmTMB - covariance structure

Yes.

   While the distribution of conditional modes is certainly not assumed
to be exactly N(0,s^2), informally, if the observed distribution of
conditional modes is far from zero-centered Gaussian, I might worry
about misspecification of the model.  I know of the existence of a
literature on the diagnosis and effects of model misspecification
(especially of the distribution of conditional modes) in (G)LMMs -- e.g.
go to http://bbolker.github.io/mixedmodels-misc/glmmbib.html and search
for "misspec" -- but I don't know its contents well at all.

 (1) adding group-level covariates (to explain some of the non-Normal
among-group variability) can help, if you have any such information
 (2) one more question about your random-effect specification.  Is time
being treated as categorical or continuous?
   If categorical:
     - if there are n time points, us(time+0|Subject) will have
n*(n+1)/2 parameters, which could get out of hand (you'll be trying to
estimate the full variance-covariance matrix among all n observations
for each subject -- you'll need lots of subjects to make this work).
Could be worth trying an ar1() model instead?
     - allowing for a *continuous*, fixed effect of time in addition to
the random effect could help (again, by explaining some of the
systematic variability)
   - if continuous: I'm not sure why you would suppress the intercept
variation?
On 2018-09-06 02:42 PM, D. Rizopoulos wrote: