random effects estimation in Lmer
On Tue, 15 Dec 2009, Henric (Nilsson) Winell wrote:
On 2009-12-15 09:23, David Duffy wrote:
Have you looked at the kinship package at all? It uses lme, but analyses age at onset data from families more nicely than lmer can (see the coxme() function and the vignette/documentation).
Actually, the latest version of the coxme() function now lives in Terry Therneau's new 'coxme' package. It no longer depends on 'nlme', but uses its own fitting routines and sparse matrix representation, and has a lme4-like syntax for the specification of random effects.
Good to know! The OP may want to use the kinship package to generate kinship matrices, and to look at the breast cancer example therein. Cheers, David Duffy.
| David Duffy (MBBS PhD) ,-_|\ | email: davidD at qimr.edu.au ph: INT+61+7+3362-0217 fax: -0101 / * | Epidemiology Unit, Queensland Institute of Medical Research \_,-._/ | 300 Herston Rd, Brisbane, Queensland 4029, Australia GPG 4D0B994A v