Message-ID: <Pine.LNX.4.64.0912161649350.27583@orpheus.qimr.edu.au>
Date: 2009-12-16T07:01:01Z
From: David Duffy
Subject: random effects estimation in Lmer
In-Reply-To: <4B276D13.7080901@gmail.com>
On Tue, 15 Dec 2009, Henric (Nilsson) Winell wrote:
> On 2009-12-15 09:23, David Duffy wrote:
>>
>> Have you looked at the kinship package at all? It uses lme, but analyses
>> age at onset data from families more nicely than lmer can (see the coxme()
>> function and the vignette/documentation).
>
> Actually, the latest version of the coxme() function now lives in Terry
> Therneau's new 'coxme' package.
>
> It no longer depends on 'nlme', but uses its own fitting routines and sparse
> matrix representation, and has a lme4-like syntax for the specification of
> random effects.
Good to know!
The OP may want to use the kinship package to generate kinship matrices,
and to look at the breast cancer example therein.
Cheers, David Duffy.
--
| David Duffy (MBBS PhD) ,-_|\
| email: davidD at qimr.edu.au ph: INT+61+7+3362-0217 fax: -0101 / *
| Epidemiology Unit, Queensland Institute of Medical Research \_,-._/
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