Message-ID: <4B28918C.3010200@erasmusmc.nl>
Date: 2009-12-16T07:51:40Z
From: Hester Lingsma
Subject: random effects estimation in Lmer
In-Reply-To: <Pine.LNX.4.64.0912161649350.27583@orpheus.qimr.edu.au>
Dear all,
Thanks for the suggestions. I will take a look at the coxme package.
Regards,
Hester Lingsma
on 16-12-2009 08:01 David Duffy said the following:
> On Tue, 15 Dec 2009, Henric (Nilsson) Winell wrote:
>
>> On 2009-12-15 09:23, David Duffy wrote:
>>>
>>> Have you looked at the kinship package at all? It uses lme, but
>>> analyses age at onset data from families more nicely than lmer can
>>> (see the coxme() function and the vignette/documentation).
>>
>> Actually, the latest version of the coxme() function now lives in
>> Terry Therneau's new 'coxme' package.
>>
>> It no longer depends on 'nlme', but uses its own fitting routines and
>> sparse matrix representation, and has a lme4-like syntax for the
>> specification of random effects.
>
> Good to know!
>
> The OP may want to use the kinship package to generate kinship
> matrices, and to look at the breast cancer example therein.
>
> Cheers, David Duffy.
>
--
_________________________________________________
Hester F. Lingsma, MSc
Dept of Public Health
Room AE-141
Erasmus MC
P.O. Box 2040
3000 CA Rotterdam
The Netherlands
Phone: (+31) (0)10 7038458/7038460
Mobile: (+31) (0)6 26467338