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What it means for rho to be 0 in lme() when using compound symmetry

The 'default' structure is generally the unstructured positive definite
matrix. (In lme4, this constraint is loosened to positive
semi-definite). Starting from compound symmetric is already placing a
constraint and so forcing all off-diagonal elements to zero may be the
best solution *under that constraint*. (And a multiple of the identity
matrix is a stricter constraint than a diagonal matrix, even though both
have all off diagonal elements set to zero.)

A more modern take would be using something like rePCA on the full
unstructured matrix (https://arxiv.org/abs/1506.04967 or
https://doi.org/10.33016/nextjournal.100002) to see what the effective
dimensionality is. Of course, you can fit a model with a diagonal RE
covariance matrix even if the data have some correlation, at the cost of
changing how shrinkage works
(https://doingbayesiandataanalysis.blogspot.com/2019/07/shrinkage-in-hierarchical-models-random.html).
That may be an acceptable (variance-bias) tradeoff -- less efficient
shrinkage but also less overparameterization.

All of these comments without looking at your data.
On 4/12/20 4:23 pm, Simon Harmel wrote: