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[Bioc-devel] Troubles using R/Bioc-devel with Mac OS X El Capitan 10.11.1

The suggestion on R-SIG-mac in the thread I cited is that homebrew is not the right way to go. This is from very established members of the R-community (Simon Urbanek, Brian Ripley), and I would not treat it lightly.

Also, if you are installing R-devel (implied by use of Bioc 3.3), there are some recent commits (from Michael Lawrence, involving method dispatch) that might be causing problems; you'll definitely want the head of svn trunk rather than a snapshot.

Martin