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[Bioc-devel] Troubles using R/Bioc-devel with Mac OS X El Capitan 10.11.1

Probably the definitive answer will be the R-SIG-Mac mailing list

  https://stat.ethz.ch/mailman/listinfo/r-sig-mac

perhaps specifically this thread

  https://stat.ethz.ch/pipermail/r-sig-mac/2015-October/011641.html

which points to the R-admin manual and especially

  https://cran.r-project.org/doc/manuals/r-release/R-admin.html#OS-X