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Data frame index?

Hi, R users:

I have a data.frame (not a matrix), I got a vector with the same length 
as the
number of records (rows) of the data frame, and each element of
that vector is the column number (in a specific range of columns) of the 
corresponding
record that I must set to zero.

How can I  do this without a "for" loop?

Thank you for your help.

Kenneth