covariances between non normal traits
Dear Celine, dear list, That kind of multivariable modeling is (relatively) easy to do in (Win)BUGS/JAGS, by programming a logistic model for each trait, whose linear predictor could be modeled as (say) a multivariate normal. This could provide some kind of comparison standard to which you could compare other results obtained by (say) maximum likelihood (see for example the dclone package for a possible approach). I'd recommend you take a look at Gelman's & Hill's (2007) book on multilevel regression, whose part 2 discusses that kind of Bayesian modeling. Using "weakly informative" priors (e. g. inverse-Wishart priors for variances) should give you estimations (point estimates and credibility intervals) close to those of a frequentist analysis (but no p- values : for that, you'll have to do that yourself (not easily : ask Douglas Bates...) or resort to Bayes factors). HTH, Emmanuel Charpentier On Fri, 23 Mar 2012 12:22:57 +0100, Celine Teplitsky wrote?:
Dear all, I have seen this post by Arthur Gilmour in an ASReml related forum:
GLMM models have only been developed for the case of a single GLMM trait. It is difficult to conceive what is the appropriate error structure for bivariate GLMM traits when the variances are defined as functions of the mean.
I would like to know what people on this list think about these issues e.g. if we want to estimate correlations between 2 traits with a poisson distribution, are there some special issues to take into account? Thanks a lot in advance for your help, All the best Celine